Subtherapeutic ocular penetration of caspofungin and associated treatment failure in Candida albicans endophthalmitis.
نویسندگان
چکیده
Candida endophthalmitis represents the most serious ocular complication of candidemia. The pharmacokinetics and pharmacodynamics of fluconazole, amphotericin B, and flucytosine are fairly well established in endophthalmitis therapy. There remains a paucity of clinical data regarding the utility of new antimycotic agents in the treatment of fungal chorioretinitis and endophthalmitis. We report a case of clinical failure of caspofungin in the management of Candida albicans endophthalmitis associated with poor vitreous penetration.
منابع مشابه
Successful treatment of fungal endophthalmitis using intravitreal caspofungin.
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ورودعنوان ژورنال:
- Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
دوره 41 3 شماره
صفحات -
تاریخ انتشار 2005